Practice Support Services

Q: (Excluding COVID-19), what is the world's deadliest virus?

Written by Leslie D McDowell, DNP, ANP-BC, RN | Jul 22, 2025 1:00:00 PM

The answer is The Hepatitis Virus.

Hepatitis is also the leading cause of liver cancer!

 

World Hepatitis Day is July 28th

What is Hepatitis? 

An inflammation of the liver, most commonly caused by a viral infection. There are five main hepatitis viruses (A, B, C, D and E). These are of greatest concern because of the burden of illness and death they cause, and the potential for outbreaks and spread.

Different Types of Hepatitis:

A: Primarily spread when an unvaccinated person ingests food or water that is contaminated with the feces of an infected person. Does not usually cause chronic liver disease. Closely associated with unsafe water or food, inadequate sanitation, poor personal hygiene, and oral/anal sex. An effective vaccine is available.

B: Spread when an unvaccinated person is exposed to infected blood or body fluids from an infected person, including from infected mother to child at birth. A safe and effective vaccine offers 98-100% protection. Potentially life-threatening liver infection and a major global health problem. Puts people at high risk of death from cirrhosis and liver cancer.

C: As a bloodborne virus, Hepatitis C is most commonly spread through sharing needles when injecting drugs, and through sexual contact. If appropriate practices are not followed, it can also be spread via inadequate sterilization of medical equipment in healthcare settings or transfusion of unscreened blood / blood products. There is no effective vaccine against hepatitis C.

D: Infection with this strain cannot occur in the absence of hepatitis B. This co-infection is considered the most severe form of chronic viral hepatitis due to faster progression to cancer and liver-related death. Vaccination against Hepatitis B is the only way to prevent hepatitis D infection.

E: Most commonly found in countries with limited access to essential water, sanitation, hygiene and health services. (Some outbreaks have occurred in war zones and camps for refugees or internally displaced populations.) This virus is shed in the stools of infected persons and enters the human body through the intestine. A vaccine to prevent this strain is licensed in China but is not yet available elsewhere.

Did you know.......

Medicare covers Hepatitis B Screening, Hepatitis B immunization and administration, and Hepatitis C Screening ? (It also covers HIV Screening, and since HIV is also a blood-borne virus often associated with hepatitis viruses, can be transmitted through sexual contact,  (seniors ARE sexually active), it is important to offer this as well.)

Sources:

Medicare Preventive Services Quick Reference Chart

World Hepatitis Day